Sodium Hydroxide → 3-Methoxy-5-nitrobenzoic acid

HRID 1515562Notes

Reaction equation

HRID 1515562 reaction equation
CC1C=C(C=C([N+]([O-])=O)C=1)C(O)=O.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:23]=[C:24]([N+:26]([O-:28])=[O:27])[CH:25]=1)[C:19]([O:21]C)=[O:20].[OH-].[Na+]>>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:23]=[C:24]([N+:26]([O-:28])=[O:27])[CH:25]=1)[C:19]([OH:21])=[O:20]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 877382Methyl 3-methoxy-5-nitrobenzoateHCID 221685843-Methyl-5-nitrobenzoic acid

Product 1

HCID 53002123-Methoxy-5-nitrobenzoic acid

Procedure

Using a procedure analogous to that described for the preparation of 89B, 93B was reacted with sodium hydroxide to give 93C. LC/MS 198 (M+H).

Sources & evidence

ORD record
ord-c1717e3c4f934739b61df206b4e1bb5e
Source dataset
uspto-grants-2012_07
Patent number
US08222453B2

Reaction notes

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