HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-Amino-5-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Methoxy-5-nitrobenzoic acid | HCID 5300212 | — |
| Reactant | 3-Amino-5-methylbenzamide | HCID 53988441 | — |
| Product | 3-Amino-5-methoxybenzamide | HCID 59479527 | — |
Reaction Steps
Using a procedure analogous to that described for preparation of 89C, 93C was converted to an acid chloride, reacted with aqueous ammonia, and hydrogenated to give 93D. 1H NMR (400 MHz, CD3OD) δ ppm 3.76 (s, 3H) 6.45 (t, J=2.20 Hz, 1H) 6.71-6.74 (m, 1H) 6.77 (t, J=1.54 Hz, 1H); LC/MS 167 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222453B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-360195d0424a4fbca9f6be6c9c9e8758 |
| Source note | uspto-grants-2012_07 |