HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethoxyphenylboronic acid → HCID 59479434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethoxyphenylboronic acid | HCID 2734702 | — |
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Reactant | 4-Aminopyridine-2-carboxamide | HCID 23131262 | — |
| Reactant | 2-(3-Carbamoyl-4-fluorophenylamino)-2-(3,4-dimethoxyphenyl)acetic acid | HCID 59479392 | — |
| Product | HCID 59479434 | HCID 59479434 | 63% |
Reaction Steps
99C was prepared in a procedure similar to that of 13A using 99B, 3,4-dimethoxyphenylboronic acid and glyoxylic acid monohydrate. Yield: 63%. 1H NMR (400 MHz, Methanol-d4) δ ppm 3.83 (s, 3H) 3.84 (s, 3H) 5.45 (s, 1H) 6.95-7.01 (m, 2H) 7.05-7.11 (m, 3H) 8.11 (d, J=6.59 Hz, 1H); LCMS: 331 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222453B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-5afb5706e8054e3a9709256382c52178 |
| Source note | uspto-grants-2012_07 |