Pyridine → HCID 25267405, compound

Participants

Reaction Steps

To a stirring solution of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl sulfoximide (0.5 g, 0.001 mol) and pyridine (2 mL) in DCM (20 mL) was added Chloroacetyl chloride (244 mg, 0.00215 mol) at 0° C. After few minutes, reaction mixture was diluted with water (10 ml). Organic layer was separated, dried and distilled out to get 300 mg of desired product in 52% yield.

Provenance & Evidence