Acetyl chloride → HCID 25268454, compound

HRID 1516402Notes

Reaction equation

HRID 1516402 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:12]=2[NH:18][C:19]([C:21]2[CH:26]=[CH:25][C:24]([S:27]([CH3:38])(=[N:29][C:30]([CH:32]3[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]3)=[O:31])=[O:28])=[CH:23][CH:22]=2)=[O:20])=[O:10])=[N:6][CH:7]=1.[C:39](Cl)(=[O:41])[CH3:40]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:12]=2[NH:18][C:19]([C:21]2[CH:22]=[CH:23][C:24]([S:27]([CH3:38])(=[N:29][C:30]([CH:32]3[CH2:37][CH2:36][N:35]([C:39](=[O:41])[CH3:40])[CH2:34][CH2:33]3)=[O:31])=[O:28])=[CH:25][CH:26]=2)=[O:20])=[O:10])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 25268097HCID 25268097, compound

Product 1

HCID 25268454HCID 25268454, compoundYield 87%

Procedure

Product of Example 25 was acetylated using standard N-acetylating procedure with acetyl chloride to give titled compound in 87% yield.

Sources & evidence

ORD record
ord-ed98dfd1b0ed47eca438c092bb860edf
Source dataset
uspto-grants-2012_07
Patent number
US08227492B2

Reaction notes

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