Potassium Hydroxide → HCID 607758, compound

HRID 1516410Notes

Reaction equation

HRID 1516410 reaction equation
[SH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[OH-].[K+].Cl[CH:14]([OH:16])[CH3:15]>CO>[OH:16][CH2:14][CH2:15][S:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 957384-Mercaptobenzoic acidHCID 126390351-Chloroethan-1-ol

Product 1

HCID 607758HCID 607758, compoundYield 62,566.398%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred solution of 4-mercapto benzoic acid (10 g, 0.0645 mmol) in methanol (100 mL) was added KOH (10.8 g, 0.1935 mol) at 25-30° C. Chloroethanol (10.3 g, 0.1290 mol) was then added to it. Reaction mixture was refluxed for 4 hr. Excess methanol was evaporated and then quenched in dil.HCl. Product obtained was filtered. Drying afforded 8 g of titled compound in 62% yield.

Workup

  1. customReaction mixture
  2. temperaturewas refluxed for 4 hr
  3. customExcess methanol was evaporated
  4. customquenched in dil
  5. customProduct obtained
  6. filtrationwas filtered
  7. customDrying

Sources & evidence

ORD record
ord-74f603f8de3943c88521262d87980a7b
Source dataset
uspto-grants-2012_07
Patent number
US08227492B2

Reaction notes

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