HCID 62489723, compound → HCID 25265668, compound

HRID 1516543Notes

Reaction equation

HRID 1516543 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[Cl:21][C:22]1[C:23]([NH:31][CH2:32][CH2:33][OH:34])=[N:24][CH:25]=[C:26]([CH:30]=1)[C:27](O)=[O:28]>>[Cl:21][C:22]1[C:23]([NH:31][CH2:32][CH2:33][OH:34])=[N:24][CH:25]=[C:26]([CH:30]=1)[C:27]([NH:20][C:3]1[CH:4]=[CH:5][C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)=[CH:7][C:2]=1[CH3:1])=[O:28]

Participants

3

Reactant 2

HCID 62489723HCID 62489723, compoundHCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine

Product 1

HCID 25265668HCID 25265668, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 5-chloro-6-(2-hydroxy-ethylamino)-nicotinic acid. MS: 472.3 (M+H).

Sources & evidence

ORD record
ord-f21ae416ba0c4168b2c57cfe1656fc88
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

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