2-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine → HCID 178428007, 화합물

HRID 1516544노트

반응식

HRID 1516544 반응식
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[Cl:21][C:22]1[CH:31]=[C:30]2[C:25]([C:26]([OH:35])=[C:27]([C:32](O)=[O:33])[CH:28]=[N:29]2)=[CH:24][CH:23]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:20][C:32]([C:27]1[CH:28]=[N:29][C:30]2[C:25]([C:26]=1[OH:35])=[CH:24][CH:23]=[C:22]([Cl:21])[CH:31]=2)=[O:33]

참가 물질

3

반응물 2

HCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamineHCID 178524720HCID 178524720, 화합물

생성물 1

HCID 178428007HCID 178428007, 화합물

실험 절차

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 7-chloro-4-hydroxy-quinoline-3-carboxylic acid. MS: 479.2 (M+H).

출처 및 근거

ORD 기록
ord-464684eeabfa40cfb1fbbf77c72126a9
출처 데이터셋
uspto-grants-2012_07
특허 번호
US08227504B2

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