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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1516548Generated: November 4, 2026

1,3-Benzodioxole-5-carboxylic acid → Benzo[1,3]dioxole-5-carboxylic acid {2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenyl}-amide

https://huagongshe.com/reaction/1516548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carboxylic acidHCID 7196—
Reactant2-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamineHCID 68467642—
ProductBenzo[1,3]dioxole-5-carboxylic acid {2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenyl}-amideHCID 25263720—

Reaction Steps

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with benzo[1,3]dioxole-5-carboxylic acid. MS: 422.5 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08227504B2
Source datasetuspto-grants-2012_07
ORD IDord-1784aa6a10c64a2da48675f9aacba2a5
Source noteuspto-grants-2012_07