HCID 67401293, compound → HCID 25265521, compound

HRID 1516551Notes

Reaction equation

HRID 1516551 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[C:21]([N:24]1[CH2:29][CH2:28][CH2:27][CH:26]([C:30]2[CH:38]=[CH:37][C:33]([C:34](O)=[O:35])=[CH:32][CH:31]=2)[CH2:25]1)(=[O:23])[CH3:22]>>[C:21]([N:24]1[CH2:29][CH2:28][CH2:27][CH:26]([C:30]2[CH:31]=[CH:32][C:33]([C:34]([NH:20][C:3]3[CH:4]=[CH:5][C:6]([N:8]4[CH2:12][CH2:11][CH:10]([CH2:13][N:14]5[CH2:18][CH2:17][CH2:16][CH:15]5[CH3:19])[CH2:9]4)=[CH:7][C:2]=3[CH3:1])=[O:35])=[CH:37][CH:38]=2)[CH2:25]1)(=[O:23])[CH3:22]

Participants

3

Reactant 2

HCID 67401293HCID 67401293, compoundHCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine

Product 1

HCID 25265521HCID 25265521, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 4-(1-acetyl-piperidin-3-yl)-benzoic acid. MS: 503.3 (M+H).

Sources & evidence

ORD record
ord-62a16e8241204970b0ddf5259846cfc7
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

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