4-(Hydroxymethyl)benzoic acid → HCID 25265520, compound

HRID 1516552Notes

Reaction equation

HRID 1516552 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[OH:21][CH2:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](O)=[O:28])=[CH:25][CH:24]=1>>[OH:28][CH2:27][C:26]1[CH:30]=[CH:31][C:23]([C:22]([NH:20][C:3]2[CH:4]=[CH:5][C:6]([N:8]3[CH2:12][CH2:11][CH:10]([CH2:13][N:14]4[CH2:18][CH2:17][CH2:16][CH:15]4[CH3:19])[CH2:9]3)=[CH:7][C:2]=2[CH3:1])=[O:21])=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 763604-(Hydroxymethyl)benzoic acidHCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine

Product 1

HCID 25265520HCID 25265520, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 4-hydroxymethyl-benzoic acid. MS: 408.5 (M+H).

Sources & evidence

ORD record
ord-87874aa15f4845c49a3d60bba4856049
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

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