5-Methoxyindole-2-carboxylic acid → HCID 25263580, compound

HRID 1516553Notes

Reaction equation

HRID 1516553 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[CH3:21][O:22][C:23]1[CH:24]=[C:25]2[C:29](=[CH:30][CH:31]=1)[NH:28][C:27]([C:32](O)=[O:33])=[CH:26]2>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:20][C:32]([C:27]1[NH:28][C:29]2[C:25]([CH:26]=1)=[CH:24][C:23]([O:22][CH3:21])=[CH:31][CH:30]=2)=[O:33]

Participants

3

Reactant 2

HCID 204015-Methoxyindole-2-carboxylic acidHCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine

Product 1

HCID 25263580HCID 25263580, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 5-methoxy-1H-indole-2-carboxylic acid. MS: 447.5 (M+H).

Sources & evidence

ORD record
ord-627676dde9e64d3195f64f3737791f2b
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

Loading…