2-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine → HCID 178422958, compound

HRID 1516557Notes

Reaction equation

HRID 1516557 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:20].[OH:21][C:22]1[C:31]2[C:26](=[N:27][C:28]([CH3:32])=[CH:29][CH:30]=2)[N:25]=[CH:24][C:23]=1[C:33](O)=[O:34]>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:20][C:33]([C:23]1[CH:24]=[N:25][C:26]2[C:31]([C:22]=1[OH:21])=[CH:30][CH:29]=[C:28]([CH3:32])[N:27]=2)=[O:34]

Participants

3

Reactant 2

HCID 684676422-Methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamineHCID 178422970HCID 178422970, compound

Product 1

HCID 178422958HCID 178422958, compound

Procedure

The title compound was prepared in a manner substantially the same as Example 1 by coupling 2-methyl-4-[3-(2-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-phenylamine with 4-hydroxy-7-methyl-[1,8]naphthyridine-3-carboxylic acid. MS: 460.6 (M+H).

Sources & evidence

ORD record
ord-7a08acbb131c42289cdd5ed978ff3df7
Source dataset
uspto-grants-2012_07
Patent number
US08227504B2

Reaction notes

Loading…