HCID 44199202, compound → HCID 44199205, compound

HRID 1516611Notes

Reaction equation

HRID 1516611 reaction equation
ClC1C([F:20])=C(C(C2C=CC=CC=2)C2NC=NC=2)C=CC=1.Cl[C:22]1[C:23](C)=[C:24]([CH:28]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:29]2[NH:33][CH:32]=[N:31][CH:30]=2)[CH:25]=[CH:26][CH:27]=1>>[F:20][C:22]1[CH:23]=[C:24]([CH:28]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:29]2[NH:33][CH:32]=[N:31][CH:30]=2)[CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 44199202HCID 44199202, compoundHCID 44199203HCID 44199203, compound

Product 1

HCID 44199205HCID 44199205, compound

Procedure

1H NMR (CD3OD, 300 MHz) 7.61 (s, 1H), 6.8-7.38 (m, 10H), 6.51 (s, 1H), 5.42 (s, 1H). 5-[(3-Chloro-2-fluoro-phenyl)-phenyl-methyl]-1H-imidazole: 1HNMR (CD3OD, 300 MHz) 7.61 (s, 1H), 6.95-7.38 (m, 9H), 6.51 (s, 1H), 5.71 (s, 1H). 5-[(3-Chloro-2-methyl-phenyl)-phenyl-m ethyl]-1H-imidazole: 1HNMR (CD3OD, 300 MHz) δ 7.96 (s, 1H), 7.01-7.96 (m, 9H), 6.40 (s, 1H), 5.92 (s, 1H), 2.06 (s, 3H).

Sources & evidence

ORD record
ord-30f0ed42b48c44f9b71c2167d0e3cfde
Source dataset
uspto-grants-2012_07
Patent number
US08227499B2

Reaction notes

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