HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenamine, 4-bromo-N,N-diethyl- → 4-(Diethylamino)phenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenamine, 4-bromo-N,N-diethyl- | HCID 16328 | — |
| Reactant | Triisopropyl borate | HCID 21531 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 4-(Diethylamino)phenylboronic acid | HCID 21988881 | 94.6% |
Reaction Steps
In a manner similar to that of Example 1c, by reacting 5 g of (4-bromo-phenyl)diethylamine (21.9 mmol) with 13 mL of 2.0 M n-butyllithium solution and 6 mL (26 mmol) of triisopropyl borate. 4 g of 4-diethylaminophenylboronic acid (yield=94%) are obtained in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08227507B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-450781878fb442fa91ef22e35fe6365e |
| Source note | uspto-grants-2012_07 |