Cyclopropylamine → HCID 86617908, compound

Participants

Reaction Steps

In a manner similar to that of Example 38b, by reacting 490 mg of ethyl 4″-(acetylethylamino)-4′-(3-bromopropyl)-3″-tert-butyl[1,1′;3′,1″]terphenyl-4-carboxylate (0.87 mmol) with 0.6 mL of cyclopropylamine (9 mmol). 270 mg of ethyl 4″-(acetylethylamino)-3″-tert-butyl-4′-(3-cyclopropylaminopropyl)-[1,1′;3′,1″]terphenyl-4-carboxylate are obtained (yield=57%) in the form of an orange-colored oil.

Provenance & Evidence