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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1516675Generated: October 31, 2026

Benzamide → HCID 178487733, compound

https://huagongshe.com/reaction/1516675

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamideHCID 2331—
Reactant3-(Chloromethyl)pyridine hydrochlorideHCID 23394—
Reactant2-Amino-4-methoxy-3-methylbenzamideHCID 59165435—
ProductHCID 178487733HCID 17848773392%

Reaction Steps

The general procedure described in Example 8 was followed using 2-amino-4-methoxy-3-methyl benzamide as benzamide derivative and nicotinyl chloride hydrochloride as acid chloride, which gave the title compound (2.5 g, 92%), [M+H]=268.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08227407B2
Source datasetuspto-grants-2012_07
ORD IDord-c8c226b5ed014ee49e59bcdabefe715a
Source noteuspto-grants-2012_07