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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1516908Generated: October 25, 2026

1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamide → 1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-(cyclohexylmethyl)pyridin-2-yl)cyclopropanecarboxamide

https://huagongshe.com/reaction/1516908

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamideHCID 57895164—
Reactant1-(benzo[d][1,3]dioxol-5-yl)-N-(5-bromopyridin-2-yl)cyclopropanecarboxamideHCID 59166163—
ReactantHCID 178419774HCID 178419774—
Product1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-(cyclohexylmethyl)pyridin-2-yl)cyclopropanecarboxamideHCID 44236469—

Reaction Steps

1-(Benzo[d][1,3]dioxol-5-yl)-N-(5-(cyclohexylmethyl)pyridin-2-yl)cyclopropanecarboxamide was synthesized using the procedure of 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-benzylpyridin-2-yl)cyclopropanecarboxamide by reacting 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-bromopyridin-2-yl)cyclopropanecarboxamide with (cyclohexylmethyl)zinc(II) bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08227615B2
Source datasetuspto-grants-2012_07
ORD IDord-c0c03b7bee874c83bdc58f074bc85afe
Source noteuspto-grants-2012_07