HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-Pyrrolidinyl)piperidine → HCID 58016732, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-Pyrrolidinyl)piperidine | HCID 78703 | — |
| Reactant | 3-Methyl-5-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid | HCID 57441124 | — |
| Reactant | HCID 57441134 | HCID 57441134 | — |
| Reactant | HCID 57441149 | HCID 57441149 | — |
| Product | HCID 58016732 | HCID 58016732 | — |
Reaction Steps
In analogy to the procedure described for example 1, 3-chloro-5-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid [prepared from 3-chloro-5-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester (intermediate 7) by saponification in analogy to the procedure described for intermediate 1B] was reacted with 4-pyrrolidin-1-yl-piperidine to give the title compound as light yellow oil. MS: 438.2 (MH+, 1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08227613B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-71b10602cb764f468450566ad7870d05 |
| Source note | uspto-grants-2012_07 |