反应详情

In analogy to the procedure described for example 1, 3,5-bis-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid [prepared from 3,5-bis-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester (intermediate 8) by saponification in analogy to the procedure described for intermediate 1B] was reacted with 4-pyrrolidin-1-yl-piperidine to give the title compound as light yellow oil. MS: 548.3 (MH+).