反应详情

In analogy to the procedure described for the preparation of intermediate 5C, [6-chloro-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone (example 3) was reacted with pyrimidine-5-yl-boronic acid to give the title compound as off-white amorphous solid. MS: 496.2 (MH+).