HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → HCID 58016721, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 57441165 | HCID 57441165 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58016721 | HCID 58016721 | — |
Reaction Steps
In analogy to the procedure described for the preparation of example 1, 5-methyl-6-(4-pyrrolidin-1-yl-piperidine-1-carbonyl)-3-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid (example 47) was reacted with ethanolamine, Et3N and HATU in DMF to give the title compound as light yellow solid. MS: 505.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08227613B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-beacd2f9e09b439abcf080d7a1648a3b |
| Source note | uspto-grants-2012_07 |