反应详情

温度

35 °C

To 1600 ml of acetic acid are added 46.7 g (198 mM) of N-(2-nitro-4-propanoylphenyl)acetamide. To the solution obtained, heated to 35° C., is added over 2 hours a solution of 10.13 ml (198 mM) of bromine in 200 ml of acetic acid. The reaction medium is then added gently to 5000 ml of water, and a solid crystallises out. After filtering off the solid and washing with water, 56.8 g of N-[4-(2-bromopropanoyl)-2-nitrophenyl]acetamide are obtained in the form of a pale yellow solid.

1. customTo the solution obtained
2. customa solid crystallises out
3. filtrationAfter filtering off the solid
4. washwashing with water, 56.8 g of N-[4-(2-bromopropanoyl)-2-nitrophenyl]acetamide
5. customare obtained in the form of a pale yellow solid