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HRID1517215

反应详情

EQUATION

反应方程式

HRID 1517215 的结构方程式

REACTANTS

反应物

3
结构：ClC(Cl)Cl
HCID6212

Chloroform

CHCl3

结构：CCCCCCCCCCCCCCCC[n+]1ccccc1.[Cl-]
HCID31239

未命名化合物

结构：CCN1CCN(C(=O)N[C@@H](C(=O)N[C@@H]2C(=O)N3[C@@H]2SC(C)(C)[C@@H]3C(=O)[O-])c2ccccc2)C(=O)C1=O.[Na+]
HCID23666879

Piperacillin sodium

C23H26N5NaO7S

PRODUCTS

生成物

1
结构：CCCCCCCCCCCCCCCC[n+]1ccccc1.CCN1CCN(C(=O)N[C@@H](C(=O)N[C@@H]2C(=O)N3[C@@H]2SC(C)(C)[C@@H]3C(=O)O)c2ccccc2)C(=O)C1=O
HCID67382660

未命名化合物

收率 58.66%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

2 次

PROCEDURE

实验过程

Hexadecylpyridinium chloride (0.001 mol) was dissolved in 60 mL of distilled water by gentle heating and stirring. Sodium piperacillin (0.001 mol) was dissolved in 60 mL of distilled water by gentle heating and stirring. The two solutions were combined and the reaction mixture was heated and stirred for 30 minutes. The reaction mixture cooled to room temperature, and then 60 mL of chloroform was added. The reaction mixture was stirred for an additional 30 minutes. The two phases were separated and the chloroform phase was washed several times with cool distilled water to remove any inorganic salt. The presence of chloride anions was monitored by silver nitrate test. A rotary evaporator removed the chloroform and a soft orange solid was obtained in 58.66% yield. Melting point (hot plate apparatus)=30-40° C.

WORKUP

后处理

  1. temperatureby gentle heating
  2. temperatureby gentle heating
  3. stirringstirring
  4. temperaturethe reaction mixture was heated
  5. stirringstirred for 30 minutes
  6. stirringThe reaction mixture was stirred for an additional 30 minutes
  7. customThe two phases were separated
  8. washthe chloroform phase was washed several times
  9. temperaturewith cool
  10. distillationdistilled water
  11. customto remove any inorganic salt
  12. customA rotary evaporator
  13. customremoved the chloroform
  14. customa soft orange solid was obtained in 58.66% yield
  15. customMelting point (hot plate apparatus)=30-40° C.