2-Fluoro-5-(trifluoromethyl)phenol → N-[3-(1-{6-[2-Fluoro-5-(trifluoromethyl)phenoxy]-6-phenylhexyl}-4-piperidinyl)phenyl]-2-methylpropanamide
Reaction equation
[F:1][c:2]1[c:3]([OH:12])[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[OH:13][CH:14]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][N:20]1[CH2:21][CH2:22][CH:23]([c:26]2[cH:27][c:28]([NH:32][C:33]([CH:34]([CH3:35])[CH3:36])=[O:37])[cH:29][cH:30][cH:31]2)[CH2:24][CH2:25]1)[c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[F:1][c:2]1[c:3]([O:12][CH:14]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([c:26]3[cH:27][c:28]([NH:32][C:33]([CH:34]([CH3:35])[CH3:36])=[O:37])[cH:29][cH:30][cH:31]3)[CH2:24][CH2:25]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-20c473d50c53452592300b67995f8dc2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…