6-(2-(Ethylamino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl pivalate → 6-{2-{[4-(1-Azabicyclo[2.2.2]oct-4-ylmethoxy)benzyl]ethylamino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
Reaction equation
[CH2:1]([NH:2][c:3]1[cH:4][c:5]([O:6][CH3:7])[cH:8][cH:9][c:10]1[CH:11]1[CH2:12][CH2:13][c:14]2[cH:15][c:16]([O:17][C:18](=[O:19])[C:20]([CH3:21])([CH3:22])[CH3:23])[cH:24][cH:25][c:26]2[CH2:27]1)[CH3:28].[N:29]12[CH2:30][CH2:31][C:32]([CH2:33][O:34][c:35]3[cH:36][cH:37][c:38]([CH:39]=[O:40])[cH:41][cH:42]3)([CH2:43][CH2:44]1)[CH2:45][CH2:46]2.[N:47]12[CH2:48][CH2:49][C:50]([CH2:55][O:56][c:57]3[cH:58][cH:59][c:60]([CH2:61][CH2:62][CH2:63][NH:64][c:65]4[c:66]([CH:73]5[CH2:74][c:75]6[cH:76][cH:77][c:78]([O:83][C:84](=[O:85])[C:86]([CH3:87])([CH3:88])[CH3:89])[cH:79][c:80]6[CH2:81][CH2:82]5)[cH:67][cH:68][c:69]([O:71][CH3:72])[cH:70]4)[cH:90][cH:91]3)([CH2:51][CH2:52]1)[CH2:53][CH2:54]2>>[N:47]12[CH2:48][CH2:49][C:50]([CH2:55][O:56][c:57]3[cH:58][cH:59][c:60]([CH2:61][CH2:62][CH2:63][NH:64][c:65]4[c:66]([CH:73]5[CH2:74][c:75]6[cH:76][cH:77][c:78]([OH:83])[cH:79][c:80]6[CH2:81][CH2:82]5)[cH:67][cH:68][c:69]([O:71][CH3:72])[cH:70]4)[cH:90][cH:91]3)([CH2:51][CH2:52]1)[CH2:53][CH2:54]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5108fa39ffeb4c8ba877bc486bc07675
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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