反应详情

step 3—A mixture of 62 (95 mg) and 10% Pd/C (10 mg) in MeOH (5 mL) at RT was stirred under 1 atmosphere of H2 for 0.5 h. The catalyst was filtered off, and the filtrate was concentrated. The crude residue was purified on a preparative SiO2 TLC plate developed with 8% MeOH/DCM to afford 41 mg of I-9 as a white solid.

1. filtrationThe catalyst was filtered off
2. concentrationthe filtrate was concentrated
3. customThe crude residue was purified on a preparative SiO2 TLC plate
4. customto afford 41 mg of I-9 as a white solid