Pyridinium → HCID 58268559, compound

Participants

Reaction Steps

To a solution of [1-(3-cyclopropyl-pyridin-2-yl)-3-methyl-pyrazol-4-yl]-methanol (1.1 g, 5.0 mmol) in dry dichloromethane (15 mL) is added pyridinium chlorocromate (1.2 g, 5.5 mmol) under nitrogen atmosphere. The reaction mixture is stirred at room temperature for 2 h and then filtered through celite. The filtrate is concentrated under reduced pressure. The crude mixture is purified on silica gel eluting with hexane/ethyl acetate (90:10, 80:20) to yield 0.2 g (20%) of the title compound. MS (m/z): 228 (M+1).

Provenance & Evidence