Triethylamine → HCID 69453076, compound

Participants

Reaction Steps

Suspended 50.2 mg (103 μmol) of compound from Example 21D in 10 mL methanol, added 10.4 mg (103 μmol) triethylamine, stirred the colorless solution for 10 minutes at ambient temperature, concentrated and vacuum dried. Obtained 61 mg (100% yield) of the title compound as an off-white powder. 1H NMR (methanol-d4) δ: 1.29 (t, 9H), 1.32 (s, 9H), 1.90 (m, 1H), 2.59 (m, 1H), 2.89 (m, 1H), 3.00 (m, 1H), 3.16 (q, 6H), 4.54 (d, 2H), 5.29 (t, 1H), 7.28 (s, 2H), 7.31 (s, 1H), 7.52 (t, 1H), 7.74 (d, 1H), 7.97 (d, 1H), 8.36 (s, 1H). Anal Calcd for C23H27N4O6P.1.0 triethylamine.0.7 methanol: C, 58.47; H, 7.40; N, 11.48. Found: C, 58.46; H, 7.38; N, 11.44.

Provenance & Evidence