Hydrochloric Acid → (S)-((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-aminopropanoate hydrochloride

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 1 Step 3 by using (S)—((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl-carbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-amino-propanoate (61.3 mg, 0.1 mmol) and a saturated HCl solution in EtOAc (3 mL). The title compound was obtained as a pale yellow solid (57.1 mg, 83%).

Provenance & Evidence