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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517812Generated: November 3, 2026

Succinic Acid → HCID 46937545, compound

https://huagongshe.com/reaction/1517812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSuccinic AcidHCID 1110—
Reactant(S)-((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl carbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-aminopropanoateHCID 46937494—
ProductHCID 46937545HCID 46937545—

Reaction Steps

The title compound was prepared according to the procedure described in Example 1 Step 3 by using (S)—((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl-carbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-amino-propanoate (61.3 mg, 0.1 mmol) and succinic acid (23.6 mg, 0.2 mmol, Shantou Xilong chemical factory). The title compound was obtained as a white solid (68.5 mg, 93.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08232294B2
Source datasetuspto-grants-2012_07
ORD IDord-c700bdb44e604727afb1b821cd018a2f
Source noteuspto-grants-2012_07