HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic Acid → HCID 46937545, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic Acid | HCID 1110 | — |
| Reactant | (S)-((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl carbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-aminopropanoate | HCID 46937494 | — |
| Product | HCID 46937545 | HCID 46937545 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 1 Step 3 by using (S)—((R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl-carbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-amino-propanoate (61.3 mg, 0.1 mmol) and succinic acid (23.6 mg, 0.2 mmol, Shantou Xilong chemical factory). The title compound was obtained as a white solid (68.5 mg, 93.7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232294B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-c700bdb44e604727afb1b821cd018a2f |
| Source note | uspto-grants-2012_07 |