Methanesulfonic Acid → (S)-((S)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl)2-aminopropanoate methanesulfonate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 13 Step 3 by using (2S)—(S)-1-(4-(4-(7-methoxyquinolin-4-yloxy)-3-fluorophenyl-carbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl2-aminopr-opanoate (61.3 mg, 0.1 mmol) and methanesulfonic acid (19.3 mg, 0.2 mmol, Shanghai RichJoint Chemical Reagents CO., Ltd). The title compound was obtained as a yellow solid (58.2 mg, 72%).

Provenance & Evidence