Acetic Acid → (R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl 2-(methylamino)acetate acetate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 39 step 3 by using (R)-1-(4-(4-(7-methoxyquinolin-4-yloxy)-3-fluorophenyl-carbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl 2-(methyl-amino)acetate (82.3 mg, 0.134 mmol) and acetic acid (31.6 mg, 0.268 mmol). The title compound was abtained as a white solid (77.5 mg, 68%).

Provenance & Evidence