L-Tartaric acid → (R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl 2-(methylamino)acetate (2R,3R)-2,3-dihydroxysuccinate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 39 step 3 by using (R)-1-(4-(4-(7-methoxyquinolin-4-yloxy)-3-fluorophenylcarbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)prop an-2-yl 2-(methylamino)acetate (82.3 mg, 0.134 mmol) and L-tartaric acid (40.2 mg, 0.268 mmol). The title compound was abtained as a white solid (90.1 mg, 88%).

Provenance & Evidence