Oxalic acid dihydrate → (R)-1-(4-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenylcarbamoyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydropyrazol-1-yl)propan-2-yl 2-(dimethylamino)acetate oxalate

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 54 step 2 by using (R)-1-(4-(4-(7-methoxyquinolin-4-yloxy)-3-fluorophenyl-carbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl 2-(dimethyl-amino)acetate (100 mg, 0.16 mmol) and oxalic acid dihydrate (60.3 mg, 0.48 mmol). The title compound was obtained as a yellow solid (98.5 mg, 84%).

Provenance & Evidence