HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66669938, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 46938058 | HCID 46938058 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 66669938 | HCID 66669938 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 59 Step 3 by using (R)-1-(4-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-ylcarbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl 2-(methylamino)acetate (100 mg, 0.168 mmol) and a saturated solution of HCl in EtOAc (10 mL). The desired compound was obtained as a yellow solid (80.7 mg, 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232294B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-da26c39c34ae4ac990bf56c636287d30 |
| Source note | uspto-grants-2012_07 |