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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517856Generated: November 3, 2026

Hydrochloric Acid → HCID 66669938, compound

https://huagongshe.com/reaction/1517856

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 46938058HCID 46938058—
SolventEthyl AcetateHCID 8857—
ProductHCID 66669938HCID 66669938—

Reaction Steps

The title compound was prepared according to the procedure described in Example 59 Step 3 by using (R)-1-(4-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-ylcarbamoyl)-2,3-dihydro-5-methyl-3-oxo-2-phenylpyrazol-1-yl)propan-2-yl 2-(methylamino)acetate (100 mg, 0.168 mmol) and a saturated solution of HCl in EtOAc (10 mL). The desired compound was obtained as a yellow solid (80.7 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08232294B2
Source datasetuspto-grants-2012_07
ORD IDord-da26c39c34ae4ac990bf56c636287d30
Source noteuspto-grants-2012_07