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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1517894Generated: November 4, 2026

HCID 66669827, compound → HCID 136346386, compound

https://huagongshe.com/reaction/1517894

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66669827HCID 66669827—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 136346386HCID 13634638699.5%

Reaction Steps

To a solution of tert-butyl 4-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-3-fluorophenylcarbamate (800 mg, 1.632 mmol) in ethanol (50 mL) was added a catalytic amount of Pd/C. The suspension was stirred at rt under H2 for 3 h. The reaction mixture was filtered, and the filtrate was concentrated in vacuo to give the title compound as a light green solid (650 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08232294B2
Source datasetuspto-grants-2012_07
ORD IDord-8d897b425bfc48c3b903d32a1d07e5ea
Source noteuspto-grants-2012_07