HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Bis(trifluoromethyl)benzaldehyde → 2-methyl-N-[3,5-bis(trifluoromethyl)phenylmethylene]-2H-tetrazole-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Bis(trifluoromethyl)benzaldehyde | HCID 136247 | — |
| Reactant | 2-methyl-2H-1,2,3,4-tetrazol-5-amine | HCID 138677 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-methyl-N-[3,5-bis(trifluoromethyl)phenylmethylene]-2H-tetrazole-5-amine | HCID 76645725 | — |
Reaction Steps
A mixture 5-amino-2-methyltetrazole (5.00 g, 50 mmol) and 3,5-bis(trifluoromethyl)benzaldehyde (19.5 g, 81 mmol) in toluene (100 mL) is stirred and refluxed for 3 hours. The resulting mixture is concentrated to give crude 2-methyl-N-[3,5-bis(trifluoromethyl)phenylmethylene]-2H-tetrazole-5-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232403B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-6862c81fe5fa462c8b68cbd07d193c96 |
| Source note | uspto-grants-2012_07 |