2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → (3-tert-Butoxycarbonylamino-2'-trifluoromethoxy-biphenyl-4-yl)-carbamic acid tert-butyl ester

Participants

Reaction Steps

The title compound was prepared from (4-bromo-2-tert-butoxycarbonylamino-phenyl)-carbamic acid tert-butyl ester (as prepared in the previous step) and 2-trifluoromethoxyphenylboronic acid according to the procedure described in Example 1, step D. 1H-NMR (400 MHz, CDCl3) δ: 7.59 (br. s., 2H), 7.37-7.42 (m, 1H), 7.26-7.34 (m, 3H), 7.24 (dd, J=8.3, 2.0 Hz, 1H), 7.00 (br. s., 1H), 6.94 (br. s., 1H), 1.52 (s, 9H), 1.50 (s, 9H).

Provenance & Evidence