反应详情

A mixture of N-[1,1-dimethyl-2-(4-nitro-phenyl)-ethyl]-propionamide (1 g, 4 mmol) and 10% palladium on charcoal (100 mg) in methanol (50 ml) was hydrogenated at atmospheric pressure. After filtration the solvent was evaporated and the residue dissolved in ethyl acetate. The solution was dried over MgSO4, filtered, and the solvent evaporated under reduced pressure to give the product as a yellow oil (800 mg, 91%).

1. filtrationAfter filtration the solvent
2. customwas evaporated
3. dissolutionthe residue dissolved in ethyl acetate
4. dry with materialThe solution was dried over MgSO4
5. filtrationfiltered
6. customthe solvent evaporated under reduced pressure