Benzylamine → HCID 68705303, compound

Participants

Reaction Steps

This compound was prepared from 14′-cyclohexyl-2,2-dimethylspiro[1,3-dioxane-5,7′-indolo[1,2-e][1,5]benzoxazocine]-11′-carboxylate (Example 2, Step 3) and benzylamine as described in Example 9. Flash chromatography (PE:EtOAc 2:1) gave a mixture of the title compound and methyl 14-cyclohexylspiro[indolo[1,2-e][1,5]benzoxazocine-7,3′-oxetane]-11-carboxylate in 65% yield. MS (ES+) m/z 521 (M+H)+.

Provenance & Evidence