Bicarbonate Ion → N-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-2-chloro-acetamide

HRID 151835Notes

Reaction equation

HRID 151835 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH2:17])[n:8](-[c:10]2[cH:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[n:9]1.[C:32](=[O:33])([OH:34])[O-:35].[Cl:24][CH2:25][C:26](=[O:27])[Cl:28].[Cl:29][CH2:30][Cl:31].[Na+:36].[cH:18]1[cH:19][cH:20][n:21][cH:22][cH:23]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:17][C:26]([CH2:25][Cl:24])=[O:27])[n:8](-[c:10]2[cH:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[n:9]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 1049PyridineHCID 6344DichloromethaneHCID 6577Chloroacetyl chlorideHCID 29741323-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-amine

Product 1

HCID 66977571N-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-2-chloro-acetamide

Sources & evidence

ORD record
ord-bffd39e3bd5b4818aea8da2eb26d357f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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