HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-(4-Benzyloxyphenoxy)ethyl]dimethylamine → 4-[2-(Dimethylamino)ethoxy]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-(4-Benzyloxyphenoxy)ethyl]dimethylamine | HCID 59447665 | — |
| Reactant | tert-butyl 5-amino-4-cyano-3-(4-hydroxyphenyl)-1H-pyrazole-1-carboxylate | HCID 136027725 | — |
| Product | 4-[2-(Dimethylamino)ethoxy]phenol | HCID 13576238 | — |
Reaction Steps
Compound 75B was prepared in a similar manner to the synthesis of compound 31F by substituting compound 31E with compound 75A: 1H NMR (DMSO-d6): δ 8.86 (s, 1H), 6.72-6.76 (m, 2H), 6.64-6.68 (m, 2H), 3.92 (d, J=5.83 Hz, 2H), 2.56 (d, J=5.83 Hz, 2H), 2.19 (s, 6H). ESI (+)/MS: 182 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08232273B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-ffa1024630b64edb955f167eab86e6a2 |
| Source note | uspto-grants-2012_07 |