Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate → HCID 25204447, compound

Participants

Reaction Steps

Example 39 was prepared according to procedures described in Example 3 substituting tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-ylthio)piperidine-1-carboxylate for tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate. 1H NMR (500 MHz, CDCl3) δ 8.09 (d, J=8.80 Hz, 2 H), 7.62 (d, J=8.80 Hz, 2 H), 7.22 (d, J=7.70 Hz, 1 H), 6.66 (d, J=1.65 Hz, 1 H), 6.27 (dd, J=7.42, 1.92 Hz, 1 H), 4.88-5.00 (m, 1H), 4.04 (app brs, 2 H), 3.47-3.58 (m, 1 H), 3.12-3.17 (m, 2 H), 3.11 (s, 3H), 2.08-2.16 (m, 2H), 1.61-1.73 (m, 2 H), 1.26 (d, J=6.05 Hz, 6 H). MS (ESI) 451 (M+H).

Provenance & Evidence