反应详情

2-Phenylaniline (5 g, 29.55 mmol) was dissolved in acetic acid (30 mL), acetic anhydride (3.62 g, 35.45 mmol) was added thereto under ice bath, and the mixture was stirred under ice bath for 2 hours. The solution was concentrated under reduced pressure. to the residue was added water (15 mL), and the mixture was stirred at room temperature for 3 hours. The precipitate was collected by filtration, washed with purified water, and dried under reduced pressure to obtain 2-phenyl-N-acetylaniline (6.21 g).

1. concentrationThe solution was concentrated under reduced pressure
2. additionto the residue was added water (15 mL)
3. stirringthe mixture was stirred at room temperature for 3 hours
4. filtrationThe precipitate was collected by filtration
5. washwashed with purified water
6. customdried under reduced pressure