HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 13844-22-9
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Escin | HCID 6433489 | — |
| Product | 13844-22-9 | HCID 612009 | — |
| Product | HCID 15558431 | HCID 15558431 | — |
Reaction Steps
In Justus Liebigs Annalen der Chemie 1963, 669, 183-188 Kuhn R. and Loew I. described the hydrolysis of escin in the solution of 4 N hydrochloric acid in ethanol, the separation of the intermediate, and its subsequent hydrolysis under basic conditions with potassium hydroxide in methanol. The hydrolysis products were separated by chromatography on silica gel, yielding protoescigenin and escigenin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073813B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-e9b74c31e05d49879ad7b2276ebe75fa |
| Source note | uspto-grants-2015_07 |