4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)morpholine → 7-(6-Morpholin-4-yl-pyridin-3-yl)-1-[5-(trifluoromethyl)furan-2-ylmethyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

HRID 151898Notes

Reaction equation

HRID 151898 reaction equation
[CH3:22][C:23]1([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28][B:29]([c:30]2[cH:31][cH:32][c:33]([N:36]3[CH2:37][CH2:38][O:39][CH2:40][CH2:41]3)[n:34][cH:35]2)[O:42]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:20][cH:21]1)[NH:6][CH2:7][CH2:8][N:9]2[CH2:10][c:11]1[o:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]1>>[c:2]1(-[c:30]2[cH:31][cH:32][c:33]([N:36]3[CH2:37][CH2:38][O:39][CH2:40][CH2:41]3)[n:34][cH:35]2)[cH:3][c:4]2[c:5]([n:20][cH:21]1)[NH:6][CH2:7][CH2:8][N:9]2[CH2:10][c:11]1[o:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]1

Participants

3

Reactant 2

HCID 27953634-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)morpholineHCID 578858467-Iodo-1-[5-(trifluoromethyl)furan-2-ylmethyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

Product 1

HCID 578861257-(6-Morpholin-4-yl-pyridin-3-yl)-1-[5-(trifluoromethyl)furan-2-ylmethyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

Sources & evidence

ORD record
ord-3e1cddf7f41742598385d763b658b6f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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