HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 90310776, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Bromo-2-tert-butylphenol | HCID 10331382 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 90310776 | HCID 90310776 | 92.4% |
Reaction Steps
5-Bromo-2-tert-butylphenol (1.08 g, 4.71 mmol), benzyl bromide (0.69 mL, 5.7 mmol) and Cs2CO3(2.3 g, 7.1 mmol) were added to 23.6 mL of acetonitrile and stirred at room temperature for 64 hours. The reaction mixture was filtered and concentrated to dryness. Purification by FCC resulted in title compound (1.39 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073876B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-012da4c8f76a47529858370c66df9ef2 |
| Source note | uspto-grants-2015_07 |