1H-Indazol-5-ol → HCID 70169902, compound

HRID 1519246Notes

Reaction equation

HRID 1519246 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[O:13][C:12]([CH:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)=[N:11][C:10]=2[CH2:20][OH:21])=[CH:4][CH:3]=1.[NH:22]1[C:30]2[C:25](=[CH:26][C:27](O)=[CH:28][CH:29]=2)[CH:24]=[N:23]1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[O:13][C:12]([CH:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)=[N:11][C:10]=2[CH2:20][O:21][C:27]2[CH:26]=[C:25]3[C:30](=[CH:29][CH:28]=2)[NH:22][N:23]=[CH:24]3)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 1014381H-Indazol-5-olHCID 70168615HCID 70168615, compound

Product 1

HCID 70169902HCID 70169902, compound

Procedure

Prepared from {5-[(4-chlorophenyl)sulfanyl]-2-(tetrahydro-2H-pyran-4-yl)-1,3-oxazol-4-yl}methanol (INTERMEDIATE C6.1) and 1H-indazol-5-ol using a similar procedure as described in the preparation of example B2.1. MS: M+H=442.

Workup

  1. customas described in the preparation of example B2.1

Sources & evidence

ORD record
ord-b42825eaec8e4df8be5eee425f5baf76
Source dataset
uspto-grants-2015_07
Patent number
US09073879B2

Reaction notes

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