Potassium Carbonate → HCID 56970634, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2,2-dimethylpiperazine (35 mg, 0.31 mmol), 1-(2-bromoethyl)-4-nitrobenzene (280 mg, 1.2 mmol), tetrabutylammonium iodide (11 mg, 0.031 mmol), and K2CO3 (169 mg, 1.2 mmol) in DMF (2 mL) was heated to 60° C. for 16 hours. LC showed formation of the desired product, which was separated by mass-directed HPLC. LC-MS (IE, m/z): 413 [M+1]+. (0.21 μm)

Provenance & Evidence